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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
07/08/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
MOURA, J. B.; VARGAS, A. C. de; GOUVEIA, G. V.; GOUVEIA, J. J. de S.; RAMOS-JÚNIOR, J. C.; BOTTON, S. de A.; PEREIRA, E. C.; COSTA, M. M. da. |
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Afiliação: |
Jusciêne B. Moura, Universidade Federal do Vale do São Francisco - Univasf/Laboratório de Microbiologia e Imunologia Animal; Agueda C. de Vargas, Universidade Federal de Santa Maria/UFSM/Laboratório de Bacteriologia - Labac, Centro de Ciências Rurais/Departamento de Medicina Veterinária Preventiva.; Gisele V. Gouveia, Universidade Federal do Vale do São Francisco - Univasf/Laboratório de Microbiologia e Imunologia Animal; João J. de S. Gouveia, Universidade Federal do Vale do São Francisco - Univasf/Laboratório de Microbiologia e Imunologia Animal; Juracy C. Ramos-Júnior, Clínica Veterinária São Francisco - Clivesf; Sônia de A. Botton, Universidade Federal de Santa Maria/UFSM/Laboratório de Bacteriologia - Labac, Centro de Ciências Rurais/Departamento de Medicina Veterinária Preventiva.; Eugênia C. Pereira, Universidade Federal de Pernambuco - UFPE,Departamento de Ciências Geográficas, Centro de Filosofia e Ciências Humanas; Mateus M. da Costa, Universidade Federal do Vale do São Francisco - Univasf/Laboratório de Microbiologia e Imunologia Animal. |
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Título: |
In vitro antimicrobial activity of the organic extract of Cladonia substellata Vainio and usnic acid against Staphylococcus spp. obtained from cats and dogs. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 4, p. 368-378, abril 2017. |
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Idioma: |
Inglês |
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Notas: |
Título em português: Atividade antimicrobiana in vitro do extrato orgânico de Cladonia substellata Vainio e ácido úsnico frente Staphylococcus spp. obtidos de cães e gatos. |
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Conteúdo: |
Cladonia substellata Vainio is a lichen found in different regions of the world, including the Northeast of Brazil. It contains several secondary metabolites with biological activity, including usnic acid, which has exhibited a wide range of biological activities. The aim of this study was to evaluate the in vitro antimicrobial activity of the organic extract of C. substellata and purified usnic acid. Initially, Staphylococcus spp., derived from samples of skin and ears of dogs and cats with suspected pyoderma and otitis, were isolated and analyzed. In antimicrobial susceptibility testing against Staphylococcus spp., 77% (105/136) of the isolates were resistant to the antimicrobials tested. In the assessment of biofilm production, 83% (113/136) were classified as producing biofilm. In genetic characterization, 32% (44/136) were positive for blaZ, no isolate (0/136) was positive for the mecA gene, and 2% (3/136) were positive for the icaD gene. The in vitro antimicrobial activity of the organic extract of C. substellata and purified usnic acid against Staphylococcus spp. ranged from 0.25mg/mL to 0.0019mg/mL, inhibiting bacterial growth at low concentrations. The substances were more effective against biofilm-producing bacteria (0.65mg/mL-0.42mg/mL) when compared to non-biofilm producing bacteria (2.52mg/mL-2.71mg/mL). Usnic acid and the organic extract of C. substellata can be effective in the treatment of pyoderma and otitis in dogs and cats caused by Staphylococcus spp. |
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Palavras-Chave: |
Antimicrobial activity; Antimicrobiano; Cladonia substellata; Lichen. |
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Thesagro: |
Bactéria; Biofilme; Cão; Gato; Gene. |
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Thesaurus Nal: |
Biofilm; Cats; Dogs; Genes; Lichens; Usnic acid. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/162500/1/In-vitro-atimicrobial-activity.pdf
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Marc: |
LEADER 02796naa a2200397 a 4500
001 2073707
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aMOURA, J. B.
245 $aIn vitro antimicrobial activity of the organic extract of Cladonia substellata Vainio and usnic acid against Staphylococcus spp. obtained from cats and dogs.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Atividade antimicrobiana in vitro do extrato orgânico de Cladonia substellata Vainio e ácido úsnico frente Staphylococcus spp. obtidos de cães e gatos.
520 $aCladonia substellata Vainio is a lichen found in different regions of the world, including the Northeast of Brazil. It contains several secondary metabolites with biological activity, including usnic acid, which has exhibited a wide range of biological activities. The aim of this study was to evaluate the in vitro antimicrobial activity of the organic extract of C. substellata and purified usnic acid. Initially, Staphylococcus spp., derived from samples of skin and ears of dogs and cats with suspected pyoderma and otitis, were isolated and analyzed. In antimicrobial susceptibility testing against Staphylococcus spp., 77% (105/136) of the isolates were resistant to the antimicrobials tested. In the assessment of biofilm production, 83% (113/136) were classified as producing biofilm. In genetic characterization, 32% (44/136) were positive for blaZ, no isolate (0/136) was positive for the mecA gene, and 2% (3/136) were positive for the icaD gene. The in vitro antimicrobial activity of the organic extract of C. substellata and purified usnic acid against Staphylococcus spp. ranged from 0.25mg/mL to 0.0019mg/mL, inhibiting bacterial growth at low concentrations. The substances were more effective against biofilm-producing bacteria (0.65mg/mL-0.42mg/mL) when compared to non-biofilm producing bacteria (2.52mg/mL-2.71mg/mL). Usnic acid and the organic extract of C. substellata can be effective in the treatment of pyoderma and otitis in dogs and cats caused by Staphylococcus spp.
650 $aBiofilm
650 $aCats
650 $aDogs
650 $aGenes
650 $aLichens
650 $aUsnic acid
650 $aBactéria
650 $aBiofilme
650 $aCão
650 $aGato
650 $aGene
653 $aAntimicrobial activity
653 $aAntimicrobiano
653 $aCladonia substellata
653 $aLichen
700 1 $aVARGAS, A. C. de
700 1 $aGOUVEIA, G. V.
700 1 $aGOUVEIA, J. J. de S.
700 1 $aRAMOS-JÚNIOR, J. C.
700 1 $aBOTTON, S. de A.
700 1 $aPEREIRA, E. C.
700 1 $aCOSTA, M. M. da
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 4, p. 368-378, abril 2017.
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